
South Carolina Lowcountry Vacations from $568
Book a Hotel + Flight or Car together to unlock savings
- Plan, book, travel with confidence
- Better togetherSave up to $2,000 when you book a flight and hotel together*
- Find the right fitWith over 300,000 hotels worldwide, it's easy to create a perfect package
- Rest easyPlan, book, and manage your trip all in one place
Your South Carolina Lowcountry Vacation
Whether you're visiting South Carolina Lowcountry for its rich history, coastal scenery or something else entirely, this is one destination you'll never forget. Create your ultimate break with one of our South Carolina Lowcountry vacation packages. With so many things to see on a trip to South Carolina Lowcountry, it can be difficult to know where to start. Kick off your journey in Beaufort at Bay Street and The Sands — two popular attractions here. Another great city worthy of a spot on your itinerary is Walterboro - St. George. Don't miss The Forde Doll & Doll House Collection and South Carolina Artisans Center. Expedia has hotels, flights and all your other travel needs to help you create your own tailored South Carolina Lowcountry vacation today.
The Latest South Carolina Lowcountry vacation packages

The Ryder Hotel
Reviewed on Oct 23, 2026


Seawatch at Island Club
Reviewed on Oct 13, 2026


Where to stay in South Carolina Lowcountry

Sea Pines
While visiting Sea Pines, you might make a stop by sights like Atlantic Dunes by Davis Love III and Harbour Town Golf Links.

Edisto Beach
You'll enjoy the beaches and riverfront in Edisto Beach. You might want to make time for a stop at Edisto Beach State Park or Plantation Course at Edisto.

South End
If you're spending some time in South End, Sea Pines Forest Preserve and Heron Point by Pete Dye at Sea Pines Resort are top sights worth seeing.

Mid Island
While visiting Mid Island, you might make a stop by sights like Shelter Cove Harbour and Singleton Beach.

North Forest Beach
While visiting North Forest Beach, you might make a stop by sights like Coligny Plaza and Coligny Beach.
Stay near popular South Carolina Lowcountry attractions

Coligny Beach

Coligny Plaza

Shelter Cove Harbour

Harbour Town Lighthouse

Sea Pines Forest Preserve

Harbour Town Golf Links
Bay Street
Palmetto Dunes Club
South Carolina Lowcountry Hotel Deals

Hilton Beachfront Resort & Spa Hilton Head Island

Palmera Inn and Suites

Sonesta Resort Hilton Head Island
Find the Best South Carolina Lowcountry Vacation Packages
South Carolina Lowcountry Essential Information
Language | English |
|---|---|
Currency | U.S dollars |
Closest Airport | Charleston Intl. Airport (CHS) |
More vacations you might like
Frequently asked questions
How do vacation package prices compare across popular destinations in the South Carolina Lowcountry?
How can I save money on a South Carolina Lowcountry vacation package?
What's included in a South Carolina Lowcountry vacation package?
Which destinations in the South Carolina Lowcountry offer the best-value vacation package deals?
When is the best time to visit the top destinations in the South Carolina Lowcountry?
What package types are available across the top destinations in the South Carolina Lowcountry?
- Budget: In Hilton Head Island, Simple Rewards Inn, rated 8.8 out of 10 by travelers, offers free breakfast and is praised for its clean rooms and good value.
- Family: Sonesta Resort Hilton Head Island, a 4-star property rated 8 out of 10 by travelers, provides family rooms and an outdoor pool, with travelers often highlighting its spacious rooms and free breakfast.
- Beach: For beach-focused trips in Hilton Head Island, Beach House Resort Hilton Head, a 4-star property rated 7.8 out of 10 by travelers, features family rooms and an outdoor pool, and travelers frequently mention the great food and good breakfast.
- Pet-friendly: In Beaufort, Home2 Suites BY Hilton Beaufort, SC, rated 8.5 out of 10 by travelers, is pet-friendly and includes a kitchenette, with travelers often praising the great breakfast and comfortable facilities.
- Couples: Beaufort Inn, a 3.5-star property rated 8.4 out of 10 by travelers, is a strong choice for couples, offering a restaurant and free breakfast, and travelers frequently praise the amazing staff and good breakfast.
Which destinations should I consider for a South Carolina Lowcountry vacation?
- For families and beach lovers: Hilton Head Island is a popular package base known for its family-friendly attractions, outdoor activities, and extensive beaches.
- For a blend of history and outdoor adventure: Beaufort offers scenic views and a range of outdoor and adventure activities, making it a great choice for families and those interested in historic charm.
- For outdoor sports and urban amenities: Bluffton provides a good base for outdoor activities and sports, alongside its city and urban attractions.
- For a quieter beach escape: Edisto Island is primarily known for its beaches, scenic views, and romantic appeal, offering more lodging choices for a relaxed getaway.
Is South Carolina Lowcountry better suited for a beach vacation or a cultural trip?
Which airports serve the main destinations in the South Carolina Lowcountry?
What are the top things to do across the destinations in the South Carolina Lowcountry?
Are there family vacation packages in the South Carolina Lowcountry with kid-friendly amenities?
- Omni Hilton Head Oceanfront Resort: In Hilton Head Island, this 4-star property, rated 8.6 out of 10 by travelers, offers family rooms and a hot tub, with travelers often praising the awesome rooms and friendly food service.
- Hilton Head Island Beach & Tennis Resort: Also in Hilton Head Island, this 3.5-star resort, rated 7.9 out of 10 by travelers, features a playground and outdoor pool, and travelers truly loved the staff.
- The Westin Hilton Head Island Resort & Spa: This 4-star Hilton Head Island property, rated 8.3 out of 10 by travelers, includes a game room and outdoor pool, with travelers highlighting the exceptional facilities and comfy rooms.
- Montage Palmetto Bluff: In Bluffton, this 5-star resort, rated 8.8 out of 10 by travelers, has family rooms and a kitchenette, with travelers praising the wonderful food and great amenities.
When should I book vacation packages for the top destinations in the South Carolina Lowcountry?
How many days do you need for a South Carolina Lowcountry vacation?
Can I change or cancel my South Carolina Lowcountry vacation package if my plans change?
Do One Key members get extra savings when booking South Carolina Lowcountry vacation packages?
Does Expedia offer Book Now, Pay Later South Carolina Lowcountry vacation packages?
How do I find last-minute vacation packages to South Carolina Lowcountry?
How does free cancellation work on South Carolina Lowcountry vacation packages?
Is it cheaper to book a South Carolina Lowcountry vacation as a package or separately?
Why should I book my South Carolina Lowcountry vacation package with Expedia?
Explore a world of travel with Expedia
- Red Roof Inn Hotels in South Carolina Lowcountry
- Hotels in Yemassee
- Privatevacationhomes in Beaufort
- 4 Star Hotels in Gardens Corner
- Apartments in Gardens Corner
- Cottages in Beaufort
- Motel 6 Hotels in South Carolina Lowcountry
- Beach in South Carolina Lowcountry
- Hotels in Beaufort
- Hotels in Walterboro
- Houseboats in South Carolina Lowcountry
- Hotels in Seabrook
- Hotels in Jacksonboro
- 5 Star Hotels in Yemassee
- Hotels in Hendersonville
- Ocean View in South Carolina Lowcountry
- Resorts in South Carolina Lowcountry
- American Airlines Detroit (DTW) to Hilton Head Island (HHH) flights
- Flights to South Carolina Lowcountry
- Flights to Yemassee
- Flights from Charlotte (CLT) to Beaufort (BFT)
- Delta Air Lines Flushing (LGA) to Hilton Head Island (HHH) flights
- Flights to Saint Helena Island
- Flights from Morrisville (RDU) to Beaufort (BFT)
- Flights to Walterboro
- Flights to Beaufort
- Flights to Ridgeland
- Where to stay in Charleston
- Edisto Island Vacations
- Where to stay in Edisto Island
- South Carolina Lowcountry All Inclusive Vacation Packages
- South Carolina Lowcountry All Inclusive Vacation Packages
- Where to stay in Walterboro
- Cypress Wetlands
- Visit Coastal South Carolina
- South Carolina Lowcountry All Inclusive Vacation Packages
- Beaufort Vacations
- Visit Sheldon
- South Carolina Lowcountry All Inclusive Vacation Packages
- Pick Pocket Plantation
- Fripp Island Vacations
- South Carolina Lowcountry All Inclusive Vacation Packages
- South Carolina Lowcountry All Inclusive Vacation Packages
- Kiawah Island Vacations
- South Carolina Lowcountry All Inclusive Vacation Packages
- Hilton Head Island Vacations
- Edisto Beach Vacations
- Visit Jacksonboro
- Saint Helena Island Vacations
- South Carolina Lowcountry All Inclusive Vacation Packages
- Where to stay in Bluffton
- Daufuskie Island Vacations
- South Carolina Lowcountry All Inclusive Vacation Packages
- South Carolina Lowcountry All Inclusive Vacation Packages
- Visit Yemassee
- Where to stay in Seabrook Island
- Where to stay in Walterboro - St. George
- Visit Islandton
- Visit Parris Island
- Palmetto Dunes Tennis
- Visit Beaufort
- Visit Edisto Island
- Where to stay in South Carolina Lowcountry
- Where to stay in Kiawah Island
- Switzerland Vacations
- Rose Hill Mansion
- Where to stay in Port Royal
- Visit Ravenel
- Visit Saint Helena Island
- Where to stay in Beaufort



















